LTD induction produces heterosynaptic LTP. (A1) EPSP amplitudes as a function of stimulation site before/after LFS at site 0. (A2) Difference between pre- vs. post-LFS response profiles for same cell. (A3) As in A2 but average of all cells (n=14). (B1) Examples of EPSPs evoked from sites 0 and 5 before/after LTD induction. Same cell as in A1-2. (B2) Time course of changes in response amplitude for same cell. (B3) As in B2 but for all cells combined. In B2-3, empty circles represent responses evoked from site 0. Filled triangles represent responses evoked from heterosynaptic sites that showed significant potentiation.